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FK506 binding protein 12-rapamycin associated protein 1
URI:
https://gptkb.org/entity/FK506_binding_protein_12-rapamycin_associated_protein_1
GPTKB entity
Statements (48)
Predicate
Object
gptkbp:instanceOf
gptkb:protein
gptkbp:alsoKnownAs
gptkb:mTOR
gptkb:FRAP1
gptkbp:associatedWith
gptkb:tuberous_sclerosis
gptkb:cancer
gptkb:diabetes
neurodegenerative diseases
gptkbp:component
gptkb:mTORC2_complex
mTORC1 complex
gptkbp:discoveredBy
gptkb:David_Sabatini
gptkbp:discoveredIn
1994
gptkbp:encodedBy
gptkb:MTOR_gene
gptkbp:enzymeCommissionNumber
2.7.11.1
gptkbp:function
regulation of cell proliferation
regulation of cell survival
regulation of transcription
regulation of cell growth
regulation of cell motility
regulation of protein synthesis
serine/threonine-protein kinase
gptkbp:gene
gptkb:MTOR
https://www.w3.org/2000/01/rdf-schema#label
FK506 binding protein 12-rapamycin associated protein 1
gptkbp:inhibitedBy
gptkb:rapamycin
FKBP12-rapamycin complex
gptkbp:locatedOnChromosome
gptkb:1p36.2
gptkbp:molecularWeight
~289 kDa
gptkbp:organism
gptkb:Homo_sapiens
gptkbp:orthologIn
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae
gptkb:Drosophila_melanogaster
gptkb:Rattus_norvegicus
gptkbp:phosphorylates
gptkb:4EBP1
gptkb:AKT1
gptkb:S6K1
gptkb:ULK1
gptkb:TFEB
gptkbp:regulates
aging
metabolism
angiogenesis
immune response
autophagy
gptkbp:subcellularLocation
gptkb:endoplasmic_reticulum
gptkb:lysosome
gptkb:nucleus
gptkb:cytoplasm
gptkbp:UniProtID
gptkb:P42345
gptkbp:bfsParent
gptkb:MTOR
gptkbp:bfsLayer
7