|
gptkbp:instanceOf
|
organelle
|
|
gptkbp:compatibleWith
|
prokaryote
plant cell (typical)
|
|
gptkbp:contains
|
gptkb:protease
gptkb:glycosidase
phosphatase
lipase
nuclease
cathepsin
acid hydrolase
hydrolytic enzyme
phospholipase
sulfatase
|
|
gptkbp:degradedBy
|
macromolecules
pathogens
cellular debris
damaged organelles
|
|
gptkbp:discoveredBy
|
gptkb:Christian_de_Duve
|
|
gptkbp:discoveredIn
|
1955
|
|
gptkbp:dysregulationAssociatedWith
|
gptkb:Tay-Sachs_disease
gptkb:Niemann-Pick_disease
gptkb:Gaucher_disease
gptkb:Pompe_disease
lysosomal storage disease
|
|
gptkbp:foundIn
|
eukaryotic cell
|
|
gptkbp:function
|
autophagy
breakdown of macromolecules
intracellular digestion
recycling of cellular components
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
lysosome
|
|
gptkbp:involvedIn
|
apoptosis
phagocytosis
endocytosis
|
|
gptkbp:markerEnzyme
|
arylsulfatase
acid phosphatase
cathepsin D
β-glucuronidase
|
|
gptkbp:membraneBound
|
true
|
|
gptkbp:originatedIn
|
gptkb:Golgi_apparatus
|
|
gptkbp:pH
|
acidic
|
|
gptkbp:presentIn
|
gptkb:Amoebozoa
animal cell
|
|
gptkbp:relatedTo
|
gptkb:endosome
gptkb:peroxisome
vacuole
|
|
gptkbp:shape
|
spherical
|
|
gptkbp:size
|
0.1–1.2 μm
|
|
gptkbp:bfsParent
|
gptkb:mTOR_pathway
gptkb:Napsin_A
gptkb:Eukaryote
|
|
gptkbp:bfsLayer
|
5
|