4EBP1

URI: https://gptkb.org/entity/4EBP1

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:PHAS-I gptkb:eIF4E-binding_protein_1
gptkbp:encodedBy	gptkb:EIF4EBP1_gene
gptkbp:Entrez_Gene_ID	gptkb:ENSG00000187840
gptkbp:fullName	gptkb:Eukaryotic_translation_initiation_factor_4E-binding_protein_1
gptkbp:function	binds eIF4E inhibits cap-dependent translation regulates translation initiation
gptkbp:gene	gptkb:EIF4EBP1
gptkbp:HGNC_ID	gptkb:HGNC:3288
gptkbp:inhibitedBy	phosphorylation
gptkbp:interactsWith	gptkb:eIF4E
gptkbp:involvedIn	gptkb:mTOR_signaling_pathway
gptkbp:locatedOnChromosome	gptkb:8p12
gptkbp:location	gptkb:cytoplasm
gptkbp:molecularWeight	12 kDa
gptkbp:OMIM	601293
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:PDB	gptkb:1WFC 2V8W
gptkbp:phosphorylates	gptkb:mTOR_pathway
gptkbp:postTranslationalModification	phosphorylation
gptkbp:RefSeq	gptkb:NP_004086
gptkbp:regulates	protein synthesis
gptkbp:relatedTo	gptkb:cancer apoptosis cell growth
gptkbp:UniProtID	gptkb:Q13541
gptkbp:bfsParent	gptkb:mTOR gptkb:mTOR_pathway
gptkbp:bfsLayer	6
https://www.w3.org/2000/01/rdf-schema#label	4EBP1