4EBP1

URI: https://gptkb.org/entity/4EBP1
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:PHAS-I
gptkb:eIF4E-binding_protein_1
gptkbp:encodedBy gptkb:EIF4EBP1_gene
gptkbp:Entrez_Gene_ID gptkb:ENSG00000187840
gptkbp:fullName gptkb:Eukaryotic_translation_initiation_factor_4E-binding_protein_1
gptkbp:function binds eIF4E
inhibits cap-dependent translation
regulates translation initiation
gptkbp:gene gptkb:EIF4EBP1
gptkbp:HGNC_ID gptkb:HGNC:3288
https://www.w3.org/2000/01/rdf-schema#label 4EBP1
gptkbp:inhibitedBy phosphorylation
gptkbp:interactsWith gptkb:eIF4E
gptkbp:involvedIn gptkb:mTOR_signaling_pathway
gptkbp:locatedOnChromosome gptkb:8p12
gptkbp:location gptkb:cytoplasm
gptkbp:molecularWeight 12 kDa
gptkbp:OMIM 601293
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB gptkb:1WFC
2V8W
gptkbp:phosphorylates gptkb:mTOR_pathway
gptkbp:postTranslationalModification phosphorylation
gptkbp:RefSeq gptkb:NP_004086
gptkbp:regulates protein synthesis
gptkbp:relatedTo gptkb:cancer
apoptosis
cell growth
gptkbp:UniProtID gptkb:Q13541
gptkbp:bfsParent gptkb:PI3K/AKT/mTOR_pathway
gptkb:mTOR_pathway
gptkbp:bfsLayer 5