Statements (161)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:mTOR
|
| gptkbp:alternativeName |
gptkb:S6K-beta-1
gptkb:p70S6K gptkb:p70_ribosomal_S6_kinase |
| gptkbp:enzymeCommissionNumber |
2.7.11.1
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:fullName |
gptkb:Ribosomal_protein_S6_kinase_beta-1
|
| gptkbp:function |
regulation of protein synthesis
serine/threonine kinase |
| gptkbp:gene |
gptkb:RPS6KB1
|
| https://www.w3.org/2000/01/rdf-schema#label |
S6K1
|
| gptkbp:inhibitedBy |
gptkb:rapamycin
|
| gptkbp:locatedOnChromosome |
17q23.1
|
| gptkbp:molecularWeight |
70 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
gptkb:type_2_diabetes obesity |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:pathway |
gptkb:mTOR_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway |
| gptkbp:phosphorylates |
gptkb:ribosomal_protein_S6
Ser371 Ser411 Ser424 Ser427 Ser447 Ser452 Ser491 Ser494 Ser498 Ser505 Ser511 Ser515 Ser520 Ser527 Ser530 Ser535 Ser540 Ser544 Ser548 Ser552 Ser556 Ser560 Ser564 Ser568 Ser572 Ser576 Ser580 Ser584 Ser588 Ser592 Ser596 Ser600 Ser604 Ser608 Ser612 Ser616 Ser620 Ser624 Ser628 Ser632 Ser636 Ser640 Ser644 Ser648 Ser652 Ser656 Ser660 Ser664 Ser668 Ser672 Ser676 Ser680 Ser684 Ser688 Ser692 Ser696 Ser700 Ser704 Ser708 Ser712 Ser716 Ser720 Ser724 Ser728 Ser732 Ser736 Ser740 Ser744 Ser748 Ser752 Ser756 Ser760 Ser764 Ser768 Ser772 Ser776 Ser780 Ser784 Ser788 Ser792 Ser796 Ser800 Ser804 Ser808 Ser812 Ser816 Ser820 Ser824 Ser828 Ser832 Ser836 Ser840 Ser844 Ser848 Ser852 Ser856 Ser860 Ser864 Ser868 Ser872 Ser876 Ser880 Ser884 Ser888 Ser892 Ser896 Ser900 Ser904 Ser908 Ser912 Ser916 Ser920 Ser924 Ser928 Ser932 Ser936 Ser940 Ser944 Ser948 Ser952 Ser956 Ser960 Ser964 Ser968 Ser972 Ser976 Ser980 Ser984 Ser988 Ser992 Ser996 Thr389 |
| gptkbp:role |
cell proliferation
metabolism cell growth insulin signaling |
| gptkbp:UniProtID |
P23443
|
| gptkbp:bfsParent |
gptkb:mTOR_pathway
|
| gptkbp:bfsLayer |
5
|