|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Elk-1
gptkb:ETS_domain-containing_protein_Elk-1
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
prostate cancer
schizophrenia
|
|
gptkbp:biologicalProcess
|
cell proliferation
protein binding
DNA binding
transcription, DNA-templated
transcription factor activity, sequence-specific DNA binding
regulation of transcription from RNA polymerase II promoter
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000198901
|
|
gptkbp:function
|
transcription factor
binds to serum response element (SRE)
regulates immediate early gene expression
|
|
gptkbp:gene
|
gptkb:ELK1
|
|
gptkbp:HGNC_ID
|
HGNC:3321
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ELK1 HUMAN
|
|
gptkbp:interactsWith
|
gptkb:GSK3B
gptkb:MAPK1
gptkb:MAPK3
gptkb:MAPK9
gptkb:CREBBP
gptkb:HDAC2
gptkb:SUMO1
gptkb:SUMO2
gptkb:SUMO3
gptkb:SRF
gptkb:MAPK14
gptkb:MAPK8
gptkb:HDAC1
|
|
gptkbp:length
|
428 amino acids
|
|
gptkbp:locatedOnChromosome
|
X
|
|
gptkbp:location
|
gptkb:Xq12
|
|
gptkbp:memberOf
|
gptkb:ETS_transcription_factor_family
TCF subfamily
|
|
gptkbp:molecularWeight
|
43 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Elk1
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:p38_MAPK_pathway
gptkb:JNK_cascade
ERK1/2 cascade
|
|
gptkbp:PDB
|
1CJT
1DUX
1K6O
|
|
gptkbp:phosphorylates
|
gptkb:MAPK1
gptkb:MAPK3
gptkb:MAPK9
gptkb:MAPK14
gptkb:MAPK8
Ser383
Ser389
|
|
gptkbp:RefSeq
|
NP_001241.1
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
gptkb:P19419
|
|
gptkbp:bfsParent
|
gptkb:Elk-1
|
|
gptkbp:bfsLayer
|
7
|