Abelson murine leukemia viral oncogene homolog 1

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:gene
gptkbp:alternativeName	gptkb:ABL_proto-oncogene_1,_non-receptor_tyrosine_kinase gptkb:c-ABL
gptkbp:associatedWith	gptkb:leukemia gptkb:chronic_myeloid_leukemia
gptkbp:biologicalProcess	apoptosis cell differentiation signal transduction cell division ATP binding protein kinase activity protein binding
gptkbp:cellularComponent	gptkb:nucleus gptkb:cytoplasm
gptkbp:discoveredBy	Herbert Abelson
gptkbp:encodes	ABL1 protein
gptkbp:Entrez_Gene_ID	25 ENSG00000097007
gptkbp:function	tyrosine kinase activity
gptkbp:HGNC_ID	HGNC:76
gptkbp:locatedOnChromosome	gptkb:chromosome_9
gptkbp:mutationAssociatedWith	gptkb:Philadelphia_chromosome
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:orthologIn	v-abl oncogene
gptkbp:PDB	1OPL
gptkbp:symbol	gptkb:ABL1
gptkbp:targetOfDrug	gptkb:bosutinib gptkb:dasatinib gptkb:ponatinib gptkb:imatinib gptkb:nilotinib
gptkbp:UniProtID	P00519
gptkbp:bfsParent	gptkb:ABL1_gene gptkb:BCR-ABL_fusion_gene gptkb:Abl
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	Abelson murine leukemia viral oncogene homolog 1