Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
chromosomal abnormality
|
| gptkbp:alsoKnownAs |
Ph chromosome
|
| gptkbp:associatedWith |
gptkb:chronic_myelogenous_leukemia
leukemia |
| gptkbp:cause |
uncontrolled cell division
|
| gptkbp:diagnosedBy |
leukemia
|
| gptkbp:discoveredBy |
David Hungerford
Peter Nowell |
| gptkbp:discoveredIn |
1960
|
| gptkbp:firstIdentifiedAt |
gptkb:University_of_Pennsylvania
|
| gptkbp:frequencyInCML |
over 90%
|
| https://www.w3.org/2000/01/rdf-schema#label |
Philadelphia chromosome
|
| gptkbp:involvedIn |
gptkb:ABL1
gptkb:BCR |
| gptkbp:location |
chromosome 22
|
| gptkbp:namedAfter |
gptkb:Philadelphia
|
| gptkbp:producesFusionGene |
gptkb:BCR-ABL
|
| gptkbp:result |
translocation
|
| gptkbp:specificTranslocation |
t(9;22)(q34;q11)
|
| gptkbp:target |
gptkb:imatinib
tyrosine kinase inhibitors |
| gptkbp:bfsParent |
gptkb:BCR-ABL
gptkb:chronic_myeloid_leukemia |
| gptkbp:bfsLayer |
6
|