|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activeState
|
GTP-bound
|
|
gptkbp:composedOf
|
small GTPases
|
|
gptkbp:database
|
gptkb:InterPro:_IPR001806
gptkb:Pfam:_PF00071
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:foundIn
|
eukaryotes
|
|
gptkbp:function
|
molecular switches
|
|
gptkbp:hasBiologicalActivity
|
GTPase activity
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ras superfamily
|
|
gptkbp:inactiveState
|
GDP-bound
|
|
gptkbp:involvedIn
|
cell signaling
|
|
gptkbp:memberOf
|
GTP-binding proteins
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
|
|
gptkbp:namedAfter
|
gptkb:Ras_protein
|
|
gptkbp:regulates
|
gptkb:GDIs_(guanine_nucleotide_dissociation_inhibitors)
gptkb:GAPs_(GTPase-activating_proteins)
gptkb:GEFs_(guanine_nucleotide_exchange_factors)
cell differentiation
cell survival
cell growth
cell cytoskeleton organization
|
|
gptkbp:relatedTo
|
oncogenesis
|
|
gptkbp:structure
|
conserved G domain
|
|
gptkbp:subfamily
|
gptkb:Arf_family
gptkb:Rab_family
gptkb:Rad_family
gptkb:Ran_family
gptkb:Rho_family
gptkb:Ras_family
|
|
gptkbp:bfsParent
|
gptkb:Arf_family
gptkb:RALA
gptkb:RHEB
gptkb:RRAS2
gptkb:Rab_family
gptkb:Rho_family
gptkb:Pfam:_PF00071
gptkb:GTPase_HRas
gptkb:RAS_protein
gptkb:RalA
gptkb:RalB
gptkb:Ral_GTPases
gptkb:Ras85D
gptkb:Rheb
gptkb:Transforming_protein_p21
gptkb:small_GTPase_superfamily
gptkb:Rab_protein
|
|
gptkbp:bfsLayer
|
6
|