small G protein family

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activeState GTP-bound
gptkbp:alsoKnownAs gptkb:small_GTPase_family
gptkbp:binds gptkb:GDP
gptkb:GTP
gptkbp:contains gptkb:Ras_subfamily
Arf subfamily
Rab subfamily
Ran subfamily
Rho subfamily
gptkbp:discoveredIn 1980s
gptkbp:foundIn eukaryotes
gptkbp:function molecular switch
https://www.w3.org/2000/01/rdf-schema#label small G protein family
gptkbp:inactiveState GDP-bound
gptkbp:memberOf G protein superfamily
gptkbp:molecularWeight 20-25 kDa
gptkbp:regulates gptkb:GDIs_(guanine_nucleotide_dissociation_inhibitors)
gptkb:GAPs_(GTPase-activating_proteins)
gptkb:GEFs_(guanine_nucleotide_exchange_factors)
vesicle trafficking
cell growth
cell signaling
cytoskeleton organization
nuclear transport
gptkbp:relatedTo signal transduction
cell motility
membrane trafficking
oncogenesis
gptkbp:bfsParent gptkb:small_GTPase_family
gptkbp:bfsLayer 7