retinoid X receptor (RXR)

URI: https://gptkb.org/entity/retinoid_X_receptor_(RXR)
GPTKB entity
Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:protein
nuclear receptor
gptkbp:activatedBy gptkb:9-cis-retinoic_acid
gptkbp:alternativeName gptkb:NR2B1_(RXRA)
gptkb:NR2B2_(RXRB)
gptkb:NR2B3_(RXRG)
gptkbp:binds gptkb:9-cis-retinoic_acid
gptkbp:discoveredIn 1990
gptkbp:Entrez_Gene_ID gptkb:6256_(RXRA)
gptkb:6257_(RXRB)
gptkb:6258_(RXRG)
gptkbp:formsHeterodimerWith gptkb:peroxisome_proliferator-activated_receptor_(PPAR)
gptkb:farnesoid_X_receptor_(FXR)
gptkb:liver_X_receptor_(LXR)
gptkb:retinoic_acid_receptor_(RAR)
gptkb:thyroid_hormone_receptor_(TR)
gptkb:vitamin_D_receptor_(VDR)
gptkbp:foundIn humans
mammals
gptkbp:function transcription factor
https://www.w3.org/2000/01/rdf-schema#label retinoid X receptor (RXR)
gptkbp:involvedIn apoptosis
cell differentiation
development
metabolism
immune response
gptkbp:locatedOnChromosome gptkb:chromosome_1_(RXRG)
gptkb:chromosome_6_(RXRB)
gptkb:chromosome_9_(RXRA)
gptkbp:product gptkb:RXR_gene
gptkbp:regulates gene expression
gptkbp:relatedTo gptkb:cancer
gptkb:diabetes
atherosclerosis
lipid metabolism
neurodegenerative diseases
retinoic acid signaling pathway
gptkbp:structure DNA-binding domain
ligand-binding domain
gptkbp:subspecies gptkb:RXR_alpha
gptkb:RXR_beta
gptkb:RXR_gamma
gptkbp:symbol gptkb:RXR
gptkbp:target gptkb:alitretinoin
gptkb:rexinoids
gptkb:bexarotene
gptkbp:UniProtID gptkb:P19793_(RXRA)
P28702 (RXRB)
P48443 (RXRG)
gptkbp:bfsParent gptkb:LXR
gptkbp:bfsLayer 6