thyroid hormone receptor (TR)
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
nuclear receptor
|
| gptkbp:activatedBy |
thyroid hormones
|
| gptkbp:associatedWith |
gptkb:thyroid_hormone_resistance_syndrome
|
| gptkbp:binds |
gptkb:triiodothyronine_(T3)
hormone thyroxine (T4) |
| gptkbp:discoveredIn |
1986
|
| gptkbp:encodedBy |
THRB gene
THRA gene |
| gptkbp:formsComplexWith |
gptkb:retinoid_X_receptor_(RXR)
|
| gptkbp:function |
transcription factor
|
| https://www.w3.org/2000/01/rdf-schema#label |
thyroid hormone receptor (TR)
|
| gptkbp:involvedIn |
development
differentiation growth metabolism regulation |
| gptkbp:ligand |
gptkb:triiodothyronine_(T3)
thyroxine (T4) |
| gptkbp:locatedIn |
cell nucleus
|
| gptkbp:memberOf |
gptkb:nuclear_hormone_receptor_family
|
| gptkbp:modulatedBy |
target gene transcription
|
| gptkbp:regulates |
gene expression
|
| gptkbp:structure |
DNA-binding domain
ligand-binding domain |
| gptkbp:subspecies |
TRα
TRβ |
| gptkbp:bfsParent |
gptkb:retinoid_X_receptor_(RXR)
|
| gptkbp:bfsLayer |
7
|