|
gptkbp:instanceOf
|
gptkb:protein
nuclear receptor
|
|
gptkbp:alternativeName
|
NR2B1
Retinoid X receptor alpha
|
|
gptkbp:binds
|
gptkb:9-cis-retinoic_acid
|
|
gptkbp:encodedBy
|
RXRA gene
|
|
gptkbp:Entrez_Gene_ID
|
6256
ENSG00000186350
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
heart
liver
adipose tissue
|
|
gptkbp:formsHeterodimerWith
|
gptkb:VDR
TR
PPAR gamma
LXR alpha
PPAR alpha
RAR alpha
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
regulates gene expression
mediates effects of retinoic acid
|
|
gptkbp:HGNC_ID
|
10477
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RXR alpha
|
|
gptkbp:involvedIn
|
gptkb:cancer
apoptosis
cell differentiation
embryonic development
lipid metabolism
|
|
gptkbp:length
|
462 amino acids
|
|
gptkbp:locatedOnChromosome
|
9q34.2
|
|
gptkbp:memberOf
|
nuclear receptor subfamily 2 group B member 1
|
|
gptkbp:molecularWeight
|
51 kDa
|
|
gptkbp:OMIM
|
180245
|
|
gptkbp:PDB
|
1FBY
|
|
gptkbp:phosphorylates
|
Ser78
Ser260
Ser49
|
|
gptkbp:RefSeq
|
NM_002957
|
|
gptkbp:target
|
gptkb:alitretinoin
gptkb:bexarotene
LGD1069
LG100268
SR11237
AGN194204
HX630
LG100754
LG101506
LGD100268
|
|
gptkbp:UniProtID
|
P19793
|
|
gptkbp:bfsParent
|
gptkb:retinoid_X_receptor_(RXR)
|
|
gptkbp:bfsLayer
|
7
|