|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
RXRB
Retinoid X receptor beta
|
|
gptkbp:associatedWith
|
cell differentiation
immune response
metabolic regulation
|
|
gptkbp:discoveredBy
|
Mangelsdorf DJ et al.
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:domain
|
DNA-binding domain
ligand-binding domain
|
|
gptkbp:encodes
|
Retinoid X receptor beta
|
|
gptkbp:Entrez_Gene_ID
|
6257
ENSG00000143171
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
gptkb:testis
brain
liver
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
transcription factor
regulation of gene expression
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
RXRB-201
RXRB-202
RXRB-203
|
|
gptkbp:HGNC_ID
|
10481
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NR2B2 (RXRB)
|
|
gptkbp:interactsWith
|
gptkb:Vitamin_D_receptor
gptkb:Thyroid_hormone_receptor
PPAR gamma
Retinoic acid receptor alpha (RARA)
Retinoic acid receptor beta (RARB)
Retinoic acid receptor gamma (RARG)
|
|
gptkbp:locatedOnChromosome
|
gptkb:6p21.3
|
|
gptkbp:memberOf
|
nuclear receptor subfamily 2 group B
|
|
gptkbp:OMIM
|
180247
|
|
gptkbp:orthologInMouse
|
Nr2b2
|
|
gptkbp:product
|
RXRB protein
|
|
gptkbp:referenceGenome
|
gptkb:GRCh38
|
|
gptkbp:regulates
|
transcription of target genes
|
|
gptkbp:significance
|
potential role in cancer
potential role in metabolic diseases
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:target
|
gptkb:9-cis-retinoic_acid
gptkb:rexinoids
retinoid ligands
|
|
gptkbp:UniProtID
|
P28702
|
|
gptkbp:bfsParent
|
gptkb:retinoid_X_receptor_(RXR)
|
|
gptkbp:bfsLayer
|
7
|