|
gptkbp:instanceOf
|
gptkb:nuclear_receptor
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:NR1I1
calcitriol receptor
|
|
gptkbp:associatedWith
|
hereditary vitamin D resistant rickets
|
|
gptkbp:binds
|
gptkb:1,25-dihydroxyvitamin_D3
|
|
gptkbp:encodedBy
|
VDR gene
|
|
gptkbp:expressedIn
|
gptkb:bone
gptkb:kidney
parathyroid gland
intestine
immune cells
|
|
gptkbp:formsComplexWith
|
gptkb:retinoid_X_receptor_(RXR)
|
|
gptkbp:foundIn
|
humans
mammals
|
|
gptkbp:function
|
regulates gene expression
mediates effects of vitamin D
|
|
gptkbp:hasPolymorphism
|
gptkb:ApaI
gptkb:BsmI
gptkb:TaqI
gptkb:FokI
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:12679
|
|
gptkbp:involvedIn
|
gptkb:metabolic_syndrome
cancer biology
autoimmune diseases
cardiovascular health
skin health
inflammatory response
insulin secretion
cellular signaling pathways
bone mineralization
hair cycle regulation
|
|
gptkbp:locatedIn
|
cell nucleus
|
|
gptkbp:locatedOnChromosome
|
chromosome 12q13.11 (human)
|
|
gptkbp:memberOf
|
nuclear receptor subfamily 1 group I member 1
|
|
gptkbp:modulatedBy
|
gptkb:immune_response
apoptosis
cell differentiation
cell proliferation
|
|
gptkbp:OMIM
|
601769
|
|
gptkbp:PDB
|
gptkb:1DB1
|
|
gptkbp:regulates
|
calcium homeostasis
phosphate metabolism
|
|
gptkbp:target
|
vitamin D analogs
|
|
gptkbp:UniProtID
|
P11473
|
|
gptkbp:bfsParent
|
gptkb:retinoid_X_receptor_(RXR)
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
vitamin D receptor (VDR)
|