Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
gptkb:vitamin_A |
gptkbp:administeredBy |
oral
topical |
gptkbp:approvedBy |
gptkb:Canada
gptkb:European_Union |
gptkbp:ATCCode |
D11AH04
|
gptkbp:CASNumber |
5300-03-8
|
gptkbp:chemicalFormula |
C20H28O2
|
gptkbp:discoveredBy |
gptkb:Hoffmann-La_Roche
|
https://www.w3.org/2000/01/rdf-schema#label |
alitretinoin
|
gptkbp:IUPACName |
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
|
gptkbp:legalStatus |
prescription only
|
gptkbp:marketedAs |
Panretin
Toctino |
gptkbp:mechanismOfAction |
retinoic acid receptor agonist
|
gptkbp:pregnancyCategory |
X (contraindicated)
|
gptkbp:relatedTo |
gptkb:isotretinoin
gptkb:tretinoin |
gptkbp:sideEffect |
headache
teratogenicity dry skin increased cholesterol lip dryness |
gptkbp:usedFor |
gptkb:Kaposi's_sarcoma
chronic hand eczema |
gptkbp:bfsParent |
gptkb:retinoid_X_receptor_(RXR)
|
gptkbp:bfsLayer |
7
|