retinoic acid receptor (RAR)
GPTKB entity
Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
transcription factor
nuclear receptor |
| gptkbp:activatedBy |
gptkb:all-trans_retinoic_acid
9-cis retinoic acid |
| gptkbp:associatedWith |
gptkb:acute_promyelocytic_leukemia
|
| gptkbp:binds |
retinoic acid
|
| gptkbp:discoveredIn |
1987
|
| gptkbp:domain |
DNA-binding domain
ligand-binding domain |
| gptkbp:encodedBy |
RARA gene
RARB gene RARG gene |
| gptkbp:formsHeterodimerWith |
gptkb:retinoid_X_receptor_(RXR)
|
| gptkbp:hasIsoform |
gptkb:RAR-alpha
RAR-beta RAR-gamma |
| https://www.w3.org/2000/01/rdf-schema#label |
retinoic acid receptor (RAR)
|
| gptkbp:involvedIn |
apoptosis
cell differentiation embryonic development immune response |
| gptkbp:ligand |
retinoic acid
|
| gptkbp:locatedIn |
cell nucleus
|
| gptkbp:memberOf |
nuclear receptor superfamily
|
| gptkbp:modulatedBy |
transcription of target genes
|
| gptkbp:regulates |
gene expression
|
| gptkbp:synonym |
gptkb:RAR
|
| gptkbp:target |
retinoid drugs
|
| gptkbp:bfsParent |
gptkb:retinoid_X_receptor_(RXR)
|
| gptkbp:bfsLayer |
7
|