|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:RXRA
Retinoid X receptor alpha
|
|
gptkbp:associatedWith
|
gptkb:cancer
apoptosis
cell differentiation
lipid metabolism
|
|
gptkbp:encodes
|
Retinoid X receptor alpha
|
|
gptkbp:Entrez_Gene_ID
|
6256
ENSG00000186350
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
heart
liver
adipose tissue
|
|
gptkbp:formsHeterodimerWith
|
Farnesoid X receptor (FXR)
Liver X receptor (LXR)
Peroxisome proliferator-activated receptor (PPAR)
Retinoic acid receptor (RAR)
|
|
gptkbp:function
|
transcription factor
nuclear receptor
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
10477
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NR2B1 (RXRA)
|
|
gptkbp:interactsWith
|
gptkb:RARA
gptkb:PPARG
gptkb:NCOA1
gptkb:NCOA2
gptkb:NCOA3
PPARA
RXRB
RXRG
|
|
gptkbp:length
|
462 amino acids
|
|
gptkbp:ligand
|
gptkb:9-cis-retinoic_acid
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_9
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
cardiomyopathy
|
|
gptkbp:OMIM
|
180245
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
1XDK
1FBY
1LBD
1MV9
|
|
gptkbp:regulates
|
gene expression
retinoic acid response elements (RAREs)
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
P19793
|
|
gptkbp:bfsParent
|
gptkb:retinoid_X_receptor_(RXR)
|
|
gptkbp:bfsLayer
|
7
|