|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:alternativeName
|
gptkb:D1R
gptkb:DRD1
gptkb:dopamine_D1_receptor
|
|
gptkbp:associatedWith
|
gptkb:Parkinson's_disease
bipolar disorder
schizophrenia
drug addiction
|
|
gptkbp:biologicalProcess
|
G-protein coupled amine receptor activity
dopamine receptor activity
dopamine receptor signaling pathway
regulation of synaptic transmission, dopaminergic
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:coupled_G_protein
|
gptkb:Gs_protein
|
|
gptkbp:drugClass
|
dopaminergic receptor
|
|
gptkbp:enemyOf
|
gptkb:A-68930
gptkb:SCH23390
gptkb:SKF-38393
gptkb:ecopipam
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000184845
1812
|
|
gptkbp:expressedIn
|
gptkb:kidney
brain
heart
retina
|
|
gptkbp:firstDescribed
|
1988
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkb:Rattus_norvegicus
|
|
gptkbp:gene
|
gptkb:DRD1
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:3023
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dopamine receptor D1
|
|
gptkbp:length
|
446
|
|
gptkbp:ligand
|
dopamine
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_5
|
|
gptkbp:major_signaling_pathway
|
gptkb:cAMP_pathway
|
|
gptkbp:molecularWeight
|
49 kDa
|
|
gptkbp:OMIM
|
126449
|
|
gptkbp:PDB
|
7LJC
|
|
gptkbp:relatedTo
|
gptkb:dopamine_receptor_D2
gptkb:dopamine_receptor_D3
gptkb:dopamine_receptor_D4
gptkb:dopamine_receptor_D5
|
|
gptkbp:signal_transduction
|
activates adenylate cyclase
|
|
gptkbp:structureType
|
seven transmembrane domain
|
|
gptkbp:UniProtID
|
gptkb:P21728
|
|
gptkbp:bfsParent
|
gptkb:Dopamine
|
|
gptkbp:bfsLayer
|
6
|