|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:activatedBy
|
gptkb:adenylate_cyclase
|
|
gptkbp:associatedWith
|
gptkb:Parkinson's_disease
gptkb:attention_deficit_hyperactivity_disorder
bipolar disorder
schizophrenia
drug addiction
hypertension
|
|
gptkbp:couples_to
|
gptkb:Gs_protein
|
|
gptkbp:discoveredBy
|
1978
|
|
gptkbp:enemyOf
|
gptkb:SCH23390
gptkb:SKF-38393
gptkb:ecopipam
A-77636
LE-300
SCH39166
dihydrexidine
|
|
gptkbp:expressedIn
|
gptkb:striatum
gptkb:kidney
brain
heart
central nervous system
limbic system
vascular smooth muscle
frontal cortex
|
|
gptkbp:foundIn
|
gptkb:human
mammals
|
|
gptkbp:gene
|
gptkb:DRD1
|
|
gptkbp:HGNC_ID
|
HGNC:3022
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dopamine D1 receptor
|
|
gptkbp:improves
|
gptkb:cAMP
|
|
gptkbp:ligand
|
dopamine
|
|
gptkbp:locatedIn
|
gptkb:cell_membrane
|
|
gptkbp:locatedOnChromosome
|
5q35.1
|
|
gptkbp:member
|
gptkb:dopamine_receptor_family
|
|
gptkbp:molecularWeight
|
49 kDa
|
|
gptkbp:number_of_amino_acids
|
446
|
|
gptkbp:OMIM
|
126449
|
|
gptkbp:PDB
|
7LJC
7CKW
7JVP
|
|
gptkbp:regulates
|
gptkb:Animalia
cognition
motor control
reward pathways
neuronal growth
|
|
gptkbp:subtype_of
|
dopamine receptor
|
|
gptkbp:UniProtID
|
gptkb:P21728
|
|
gptkbp:bfsParent
|
gptkb:dopamine_receptor_D1
|
|
gptkbp:bfsLayer
|
7
|