|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:dopamine_receptor_D1
DADR
DRD1A
Dopamine D1 receptor
|
|
gptkbp:associatedWith
|
gptkb:Parkinson's_disease
bipolar disorder
schizophrenia
drug addiction
|
|
gptkbp:biologicalProcess
|
memory
learning
regulation of blood pressure
G-protein coupled receptor activity
dopamine binding
dopaminergic synaptic transmission
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
postsynaptic membrane
|
|
gptkbp:discoveredBy
|
Kebabian JW
|
|
gptkbp:discoveredIn
|
1979
|
|
gptkbp:encodes
|
D1 dopamine receptor
|
|
gptkbp:enemyOf
|
gptkb:chlorpromazine
gptkb:SCH23390
gptkb:SKF-38393
gptkb:ecopipam
gptkb:haloperidol
dopamine
fluphenazine
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000184845
1812
|
|
gptkbp:expressedIn
|
gptkb:adrenal_gland
gptkb:kidney
brain
heart
|
|
gptkbp:function
|
dopamine receptor activity
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:3021
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DRD1
|
|
gptkbp:length
|
446 amino acids
approximately 20 kb
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_5
5q35.2
|
|
gptkbp:numberOfExons
|
2
|
|
gptkbp:OMIM
|
126449
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Drd1
|
|
gptkbp:pathway
|
gptkb:cAMP_signaling_pathway
dopaminergic synapse
|
|
gptkbp:product
|
D(1A) dopamine receptor
|
|
gptkbp:proteinFamily
|
gptkb:dopamine_receptor_family
GPCR family 1
|
|
gptkbp:recipient
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:type
|
activates adenylate cyclase
|
|
gptkbp:UniProtID
|
gptkb:P21728
|
|
gptkbp:bfsParent
|
gptkb:dopamine_receptor_D1
|
|
gptkbp:bfsLayer
|
7
|