|
gptkbp:instanceOf
|
neurotransmitter
catecholamine
monoamine
|
|
gptkbp:actsOn
|
gptkb:dopamine_receptor_D1
gptkb:dopamine_receptor_D2
gptkb:dopamine_receptor_D3
gptkb:dopamine_receptor_D4
gptkb:dopamine_receptor_D5
|
|
gptkbp:administeredBy
|
intravenous injection
|
|
gptkbp:biosynthesized_from
|
gptkb:L-DOPA
|
|
gptkbp:CASNumber
|
51-61-6
|
|
gptkbp:chemicalFormula
|
C8H11NO2
|
|
gptkbp:degraded_by_enzyme
|
gptkb:catechol-O-methyl_transferase
gptkb:monoamine_oxidase
|
|
gptkbp:discoveredBy
|
gptkb:George_Barger
gptkb:James_Ewens
|
|
gptkbp:discoveredIn
|
1910
|
|
gptkbp:foundIn
|
gptkb:human
central nervous system
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Dopamine
|
|
gptkbp:involves
|
addiction
pleasure
learning
motivation
motor control
arousal
reward system
|
|
gptkbp:IUPACName
|
4-(2-aminoethyl)benzene-1,2-diol
|
|
gptkbp:meltingPoint
|
128 °C
|
|
gptkbp:molecularWeight
|
153.18 g/mol
|
|
gptkbp:predecessor
|
norepinephrine
epinephrine
|
|
gptkbp:producedBy
|
gptkb:ventral_tegmental_area
substantia nigra
hypothalamus
|
|
gptkbp:related_disorder
|
gptkb:Parkinson's_disease
gptkb:depression
addiction
bipolar disorder
schizophrenia
ADHD
|
|
gptkbp:sideEffect
|
gptkb:arrhythmia
nausea
anxiety
headache
|
|
gptkbp:solubility
|
gptkb:water
|
|
gptkbp:synthesized_by_enzyme
|
gptkb:DOPA_decarboxylase
|
|
gptkbp:usedFor
|
gptkb:drug
heart failure
bradycardia
low blood pressure
|
|
gptkbp:bfsParent
|
gptkb:Chemical_synapse
gptkb:neurotransmitter
|
|
gptkbp:bfsLayer
|
5
|