|
gptkbp:instanceOf
|
neurodegenerative disease
|
|
gptkbp:affects
|
central nervous system
substantia nigra
|
|
gptkbp:associatedWith
|
Lewy bodies
|
|
gptkbp:awarenessMonth
|
April
|
|
gptkbp:causedBy
|
loss of dopamine-producing neurons
|
|
gptkbp:characterizedBy
|
bradykinesia
postural instability
rigidity
tremor
|
|
gptkbp:complication
|
gptkb:dementia
gptkb:pneumonia
falls
|
|
gptkbp:diagnosedBy
|
clinical evaluation
neurological examination
response to levodopa
|
|
gptkbp:firstDescribed
|
gptkb:James_Parkinson
1817
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Parkinson's disease
|
|
gptkbp:ICD-10_code
|
gptkb:G20
|
|
gptkbp:MeSH_ID
|
D010300
|
|
gptkbp:namedAfter
|
gptkb:James_Parkinson
|
|
gptkbp:notableCase
|
gptkb:Michael_J._Fox
gptkb:Muhammad_Ali
|
|
gptkbp:OMIM
|
168600
|
|
gptkbp:prevalence
|
affects about 1% of people over 60
more common in people over 60
|
|
gptkbp:progression
|
progressive
chronic
|
|
gptkbp:researchOrganization
|
gptkb:Michael_J._Fox_Foundation
|
|
gptkbp:riskFactor
|
age
family history
exposure to pesticides
|
|
gptkbp:subspecies
|
gptkb:Parkinsonism
gptkb:idiopathic_Parkinson's_disease
gptkb:juvenile_Parkinson's_disease
|
|
gptkbp:symptom
|
gptkb:depression
balance problems
muscle stiffness
resting tremor
shuffling gait
sleep disturbances
slowness of movement
speech changes
writing changes
|
|
gptkbp:treatment
|
gptkb:levodopa
occupational therapy
physical therapy
speech therapy
MAO-B inhibitors
deep brain stimulation
dopamine agonists
|
|
gptkbp:bfsParent
|
gptkb:Edward_Weston
gptkb:Jack_Buck
gptkb:Jesse_Jackson
gptkb:Joan_Didion
gptkb:Owen_Chamberlain
gptkb:Paul_Bocuse
gptkb:Margaret_Bourke-White
gptkb:Linda_Ronstadt
gptkb:Department_of_Neurology
|
|
gptkbp:bfsLayer
|
4
|