Parkinson's disease

URI: https://gptkb.org/entity/Parkinson's_disease

GPTKB entity

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Statements (62)

Predicate	Object
gptkbp:instanceOf	neurodegenerative disease
gptkbp:affects	central nervous system substantia nigra
gptkbp:associatedWith	Lewy bodies
gptkbp:awarenessMonth	April
gptkbp:causedBy	loss of dopamine-producing neurons
gptkbp:characterizedBy	bradykinesia postural instability rigidity tremor
gptkbp:complication	gptkb:dementia gptkb:pneumonia falls
gptkbp:diagnosedBy	clinical evaluation neurological examination response to levodopa
gptkbp:firstDescribed	gptkb:James_Parkinson 1817
https://www.w3.org/2000/01/rdf-schema#label	Parkinson's disease
gptkbp:ICD-10_code	gptkb:G20
gptkbp:MeSH_ID	D010300
gptkbp:namedAfter	gptkb:James_Parkinson
gptkbp:notableCase	gptkb:Michael_J._Fox gptkb:Muhammad_Ali
gptkbp:OMIM	168600
gptkbp:prevalence	affects about 1% of people over 60 more common in people over 60
gptkbp:progression	progressive chronic
gptkbp:researchOrganization	gptkb:Michael_J._Fox_Foundation
gptkbp:riskFactor	age family history exposure to pesticides
gptkbp:subspecies	gptkb:Parkinsonism gptkb:idiopathic_Parkinson's_disease gptkb:juvenile_Parkinson's_disease
gptkbp:symptom	gptkb:depression balance problems muscle stiffness resting tremor shuffling gait sleep disturbances slowness of movement speech changes writing changes
gptkbp:treatment	gptkb:levodopa occupational therapy physical therapy speech therapy MAO-B inhibitors deep brain stimulation dopamine agonists
gptkbp:bfsParent	gptkb:Edward_Weston gptkb:Jack_Buck gptkb:Jesse_Jackson gptkb:Joan_Didion gptkb:Owen_Chamberlain gptkb:Paul_Bocuse gptkb:Margaret_Bourke-White gptkb:Linda_Ronstadt gptkb:Department_of_Neurology
gptkbp:bfsLayer	4