|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:associatedWith
|
gptkb:attention_deficit_hyperactivity_disorder
novelty seeking behavior
|
|
gptkbp:couples_to
|
gptkb:Gi/o_proteins
|
|
gptkbp:discoveredBy
|
1991
|
|
gptkbp:enemyOf
|
gptkb:clozapine
gptkb:haloperidol
gptkb:risperidone
dopamine
apomorphine
|
|
gptkbp:Entrez_Gene_ID
|
1815
|
|
gptkbp:expressedIn
|
brain
heart
retina
|
|
gptkbp:gene
|
gptkb:DRD4
|
|
gptkbp:hasPolymorphism
|
variable number tandem repeat (VNTR) in exon 3
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:3025
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dopamine receptor D4
|
|
gptkbp:inhibitedBy
|
gptkb:adenylate_cyclase
|
|
gptkbp:involves
|
dopaminergic signaling
|
|
gptkbp:ligand
|
dopamine
|
|
gptkbp:locatedIn
|
gptkb:cell_membrane
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
|
|
gptkbp:member
|
gptkb:dopamine_receptor_family
|
|
gptkbp:modulatedBy
|
cAMP levels
|
|
gptkbp:OMIM
|
126452
|
|
gptkbp:structure
|
seven transmembrane domains
|
|
gptkbp:target
|
antipsychotic drugs
|
|
gptkbp:UniProtID
|
gptkb:P21917
|
|
gptkbp:bfsParent
|
gptkb:Dopamine
|
|
gptkbp:bfsLayer
|
6
|