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gptkbp:instanceOf
|
UniProt accession number
|
|
gptkbp:alternativeName
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gptkb:ERBB
gptkb:HER1
mENA
NISBD2
|
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gptkbp:associatedWith
|
gptkb:cancer
gptkb:Glioblastoma
gptkb:Colorectal_cancer
Breast cancer
Non-small cell lung carcinoma
|
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gptkbp:database
|
gptkb:UniProt
|
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gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000146648
1956
|
|
gptkbp:family
|
gptkb:ErbB_family
|
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gptkbp:function
|
Receptor tyrosine kinase involved in cell proliferation
|
|
gptkbp:gene
|
gptkb:EGFR
|
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gptkbp:hasIsoform
|
Multiple
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P21728
|
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gptkbp:lastAnnotationUpdate
|
2022-02-23
|
|
gptkbp:latestReleaseVersion
|
2007-10-23
|
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gptkbp:ligand
|
gptkb:Heparin-binding_EGF-like_growth_factor
Amphiregulin
Betacellulin
Epiregulin
Transforming growth factor alpha
Epidermal growth factor
|
|
gptkbp:locatedOnChromosome
|
gptkb:7p11.2
|
|
gptkbp:molecularWeight
|
134277 Da
|
|
gptkbp:name
|
gptkb:EGFR_HUMAN
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
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gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:ErbB_signaling_pathway
|
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gptkbp:PDB
|
1M17
2GS6
2ITX
3POZ
4KRL
5HG7
|
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gptkbp:postTranslationalModification
|
Phosphorylation
Glycosylation
|
|
gptkbp:protein_existence
|
Evidence at protein level
|
|
gptkbp:protein_name
|
gptkb:Epidermal_growth_factor_receptor
|
|
gptkbp:refersTo
|
gptkb:Epidermal_growth_factor_receptor
|
|
gptkbp:RefSeq
|
NP_005219.2
|
|
gptkbp:sequence
|
1210
|
|
gptkbp:sequenceVersion
|
4
|
|
gptkbp:status
|
Reviewed
|
|
gptkbp:subcellularLocation
|
gptkb:Endosome
gptkb:Nucleus
gptkb:Cell_membrane
|
|
gptkbp:bfsParent
|
gptkb:dopamine_receptor_D1
|
|
gptkbp:bfsLayer
|
7
|