|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:AFX
gptkb:AFX-1
gptkb:AFX1
gptkb:MSTP033
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
aging
|
|
gptkbp:cytoplasmicLocalization
|
regulated by phosphorylation
|
|
gptkbp:encodes
|
gptkb:FOXO4_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:FOXO4
gptkb:ENSG00000184481
4303
|
|
gptkbp:expressedIn
|
gptkb:human
various tissues
|
|
gptkbp:fullName
|
gptkb:Forkhead_box_protein_O4
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:3817
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FOXO4
|
|
gptkbp:inhibitedBy
|
gptkb:PI3K/AKT_pathway
|
|
gptkbp:interactsWith
|
gptkb:AKT1
gptkb:p53
|
|
gptkbp:length
|
505 amino acids
|
|
gptkbp:locatedOnChromosome
|
X
|
|
gptkbp:memberOf
|
gptkb:FOXO_subfamily
gptkb:forkhead_family
|
|
gptkbp:molecularWeight
|
54 kDa
|
|
gptkbp:nuclearLocalizationSignal
|
present
|
|
gptkbp:OMIM
|
602341
|
|
gptkbp:orthologInMouse
|
gptkb:Foxo4
|
|
gptkbp:phosphorylates
|
gptkb:AKT
|
|
gptkbp:proteinFamily
|
forkhead box proteins
|
|
gptkbp:regulates
|
gptkb:DBE_(DAF-16_family_binding_element)
apoptosis
cell differentiation
DNA repair
metabolism
cellular senescence
angiogenesis
immune response
cell cycle
stem cell maintenance
autophagy
tumor suppression
oxidative stress response
cellular homeostasis
insulin signaling
|
|
gptkbp:transcriptionallyActivatedBy
|
stress signals
|
|
gptkbp:UniProtID
|
P98177
|
|
gptkbp:bfsParent
|
gptkb:AKT1
gptkb:FOXO_transcription_factors
|
|
gptkbp:bfsLayer
|
6
|