ICP0 (Herpes simplex virus protein)

GPTKB entity

Statements (24)
Predicate Object
gptkbp:instanceOf gptkb:virus
gptkbp:alternativeName IE110
Infected Cell Protein 0
gptkbp:amendedBy host chromatin
gptkbp:degradedBy cellular restriction factors
gptkbp:encodedBy gptkb:Herpes_simplex_virus
gptkbp:expressedIn immediate-early phase of infection
gptkbp:function E3 ubiquitin ligase
transcriptional regulator
gptkbp:gene gptkb:RL2
https://www.w3.org/2000/01/rdf-schema#label ICP0 (Herpes simplex virus protein)
gptkbp:inhibitedBy innate immune response
gptkbp:interactsWith gptkb:PML_protein
SUMOylated proteins
Sp100 protein
gptkbp:locale gptkb:nucleus
gptkb:cytoplasm
gptkbp:molecularWeight 110 kDa
gptkbp:roleInVirusLifeCycle reactivation from latency
initiation of lytic infection
gptkbp:species gptkb:Herpes_simplex_virus_type_1
gptkb:Herpes_simplex_virus_type_2
gptkbp:bfsParent gptkb:USP7
gptkbp:bfsLayer 7