Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
tumor necrosis factor receptor
|
| gptkbp:discoveredBy |
Immunologists
|
| gptkbp:function |
mediates cell signaling
binds tumor necrosis factor (TNF) |
| gptkbp:gene |
gptkb:TNFRSF1A
gptkb:TNFRSF1B |
| gptkbp:hasMember |
gptkb:CD30
gptkb:CD27 gptkb:CD40 gptkb:CD95_(Fas_receptor) gptkb:TNFR1 gptkb:TNFR2 |
| https://www.w3.org/2000/01/rdf-schema#label |
TNF receptor
|
| gptkbp:involvedIn |
apoptosis
inflammation immune response |
| gptkbp:ligand |
gptkb:TNF-alpha
gptkb:TNF-beta |
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:memberOf |
gptkb:tumor_necrosis_factor_receptor_superfamily
|
| gptkbp:relatedTo |
gptkb:cancer
autoimmune diseases rheumatoid arthritis inflammatory bowel disease |
| gptkbp:target |
biologic drugs
|
| gptkbp:bfsParent |
gptkb:TRAP1
gptkb:TRAF2 gptkb:death-inducing_signaling_complex |
| gptkbp:bfsLayer |
8
|