TNF-beta

GPTKB entity

Statements (22)
Predicate Object
gptkbp:instanceOf cytokine
gptkbp:alsoKnownAs gptkb:lymphotoxin_alpha
gptkbp:associatedWith autoimmune diseases
inflammatory diseases
gptkbp:discoveredBy 1960s
gptkbp:function mediates inflammatory and immune responses
gptkbp:gene gptkb:LTA
https://www.w3.org/2000/01/rdf-schema#label TNF-beta
gptkbp:locatedOnChromosome chromosome 6p21.3
gptkbp:memberOf gptkb:tumor_necrosis_factor_superfamily
gptkbp:producedBy activated lymphocytes
gptkbp:recipient TNF receptor 1
TNF receptor 2
gptkbp:regulates apoptosis
cell proliferation
cell death
immune cell differentiation
gptkbp:relatedTo gptkb:TNF-alpha
gptkbp:structure homotrimer
gptkbp:UniProtID P01374
gptkbp:bfsParent gptkb:Lymphotoxin_alpha
gptkbp:bfsLayer 6