Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:Transforming_Growth_Factor-alpha
|
| gptkbp:associated_with |
developmental processes
fibrosis cancer progression |
| gptkbp:discovered_by |
gptkb:bird
gptkb:fish gptkb:mythological_figure invertebrates vertebrates |
| gptkbp:function |
regulation of apoptosis
extracellular matrix production regulation of cell growth immune system regulation regulation of cell differentiation |
| gptkbp:has_role |
gptkb:embryonic_development
immune response wound healing cellular signaling tissue homeostasis |
| https://www.w3.org/2000/01/rdf-schema#label |
TGF-beta superfamily
|
| gptkbp:includes |
Activins
Bone morphogenetic proteins (BM Ps) Growth differentiation factors (GD Fs) Inhibins Transforming growth factor beta (TGF-beta) |
| gptkbp:is_aimed_at |
gptkb:monoclonal_antibody
biologics therapeutic agents small molecules gene therapies |
| gptkbp:is_characterized_by |
signal transduction
ligand-receptor interactions regulatory functions dimeric structure extracellular matrix interactions |
| gptkbp:is_part_of |
molecular biology
cancer biology cell signaling pathways immunology developmental biology |
| gptkbp:is_studied_in |
cell biology
genetic studies pharmacology biomedical research therapeutic development |
| gptkbp:subspecies |
Activin/ Inhibin subfamily
BMP subfamily GDF subfamily TGF-beta subfamily |