|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:transforming_growth_factor_beta_superfamily
|
|
gptkbp:composedOf
|
cytokines
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:foundIn
|
animals
|
|
gptkbp:function
|
regulation of apoptosis
regulation of cell differentiation
regulation of cell growth
regulation of embryonic development
|
|
gptkbp:GO_term
|
GO:0070848
|
|
gptkbp:hasMember
|
gptkb:Lefty
gptkb:Activin_A
gptkb:BMP2
gptkb:BMP4
gptkb:BMP7
gptkb:GDF11
gptkb:GDF8_(myostatin)
gptkb:Inhibin_A
gptkb:Müllerian_inhibiting_substance
gptkb:Nodal
gptkb:TGF-beta1
gptkb:TGF-beta2
gptkb:TGF-beta3
|
|
gptkbp:includes
|
gptkb:bone_morphogenetic_proteins
gptkb:TGF-beta
activins
growth differentiation factors
inhibins
|
|
gptkbp:mutationAssociatedWith
|
gptkb:fibrodysplasia_ossificans_progressiva
gptkb:hereditary_hemorrhagic_telangiectasia
gptkb:Marfan_syndrome
cancer progression
|
|
gptkbp:pathway
|
gptkb:SMAD_pathway
|
|
gptkbp:recipient
|
serine/threonine kinase receptors
|
|
gptkbp:regulates
|
wound healing
angiogenesis
organogenesis
stem cell maintenance
immune cell function
extracellular matrix production
|
|
gptkbp:relatedTo
|
gptkb:cancer
immune regulation
fibrosis
|
|
gptkbp:bfsParent
|
gptkb:GDF2
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TGF-beta superfamily
|