|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
OP-1
|
|
gptkbp:discoveredBy
|
John Wozney et al.
|
|
gptkbp:discoveredIn
|
1988
|
|
gptkbp:encodedBy
|
BMP7 gene
|
|
gptkbp:Entrez_Gene_ID
|
655
ENSG00000101144
|
|
gptkbp:expressedIn
|
gptkb:bone
gptkb:kidney
eye
collagen
|
|
gptkbp:fullName
|
Bone morphogenetic protein 7
|
|
gptkbp:function
|
induces bone and cartilage development
regulates cell growth and differentiation
|
|
gptkbp:gene
|
gptkb:BMP7
|
|
gptkbp:GOID
|
GO:0007179
GO:0008284
GO:0001501
GO:0001656
GO:0001657
GO:0001658
GO:0001659
GO:0001660
GO:0001661
GO:0030509
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BMP7
|
|
gptkbp:locatedOnChromosome
|
chromosome 20q13.31
|
|
gptkbp:memberOf
|
gptkb:TGF-beta_superfamily
|
|
gptkbp:molecularWeight
|
43 kDa
|
|
gptkbp:mutationAssociatedWith
|
skeletal abnormalities
eye development disorders
|
|
gptkbp:OMIM
|
112267
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:pathway
|
gptkb:SMAD_pathway
|
|
gptkbp:PDB
|
1LXI
|
|
gptkbp:recipient
|
gptkb:BMPR1A
gptkb:BMPR1B
gptkb:BMPR2
|
|
gptkbp:relatedTo
|
gptkb:BMP2
gptkb:BMP4
BMP5
BMP6
BMP8A
|
|
gptkbp:UniProtID
|
P18075
|
|
gptkbp:usedInTherapyFor
|
chronic kidney disease
bone regeneration
|
|
gptkbp:bfsParent
|
gptkb:TGF-beta_superfamily
gptkb:bone_morphogenetic_proteins
gptkb:chordin
|
|
gptkbp:bfsLayer
|
7
|