|
gptkbp:instanceOf
|
gptkb:protein
cytokine
|
|
gptkbp:alternativeName
|
gptkb:TGFB2
transforming growth factor beta-2
|
|
gptkbp:associatedWith
|
gptkb:Loeys-Dietz_syndrome
gptkb:Marfan_syndrome
congenital heart defects
|
|
gptkbp:biologicalProcess
|
embryonic development
wound healing
extracellular matrix production
|
|
gptkbp:encodedBy
|
gptkb:TGFB2_gene
|
|
gptkbp:foundIn
|
humans
other mammals
|
|
gptkbp:function
|
regulation of cell differentiation
regulation of cell growth
regulation of immune response
|
|
gptkbp:HGNC_ID
|
11768
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TGF-beta2
|
|
gptkbp:inhibitedBy
|
proliferation of epithelial cells
|
|
gptkbp:locatedOnChromosome
|
1q41
|
|
gptkbp:memberOf
|
transforming growth factor beta family
|
|
gptkbp:molecularWeight
|
~25 kDa (mature form)
|
|
gptkbp:OMIM
|
190220
|
|
gptkbp:postTranslationalModification
|
cleavage
glycosylation
|
|
gptkbp:promotion
|
fibroblast proliferation
|
|
gptkbp:recipient
|
gptkb:TGF-beta_receptor_type_I
gptkb:TGF-beta_receptor_type_II
|
|
gptkbp:regulates
|
immune cell function
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:UniProtID
|
P61812
|
|
gptkbp:bfsParent
|
gptkb:TGF-beta_signaling_pathway
gptkb:TGF-beta_superfamily
gptkb:TGF-beta_receptor
|
|
gptkbp:bfsLayer
|
7
|