|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
BMP-2
bone morphogenetic protein 2 precursor
|
|
gptkbp:associatedWith
|
gptkb:bone
gptkb:fibrodysplasia_ossificans_progressiva
|
|
gptkbp:biologicalProcess
|
embryonic development
chondrogenesis
osteogenesis
|
|
gptkbp:discoveredBy
|
Wozney JM et al.
|
|
gptkbp:discoveredIn
|
1988
|
|
gptkbp:encodedBy
|
BMP2 gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000125845
650
|
|
gptkbp:fullName
|
Bone Morphogenetic Protein 2
|
|
gptkbp:function
|
induces bone and cartilage development
|
|
gptkbp:gene
|
gptkb:BMP2
|
|
gptkbp:GOID
|
GO:0007179
GO:0008284
GO:0030509
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BMP2
|
|
gptkbp:locatedOnChromosome
|
20p12.3
|
|
gptkbp:memberOf
|
gptkb:TGF-beta_superfamily
|
|
gptkbp:molecularWeight
|
44 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Bmp2
|
|
gptkbp:PDB
|
3BMP
|
|
gptkbp:recipient
|
gptkb:BMPR1A
gptkb:BMPR1B
gptkb:BMPR2
|
|
gptkbp:signalPeptide
|
present
|
|
gptkbp:structure
|
dimer
|
|
gptkbp:UniProtID
|
P12643
|
|
gptkbp:usedInTherapy
|
bone grafts
spinal fusion
|
|
gptkbp:bfsParent
|
gptkb:TGF-beta_superfamily
gptkb:bone_morphogenetic_proteins
gptkb:NKX2-5
gptkb:BMPR1A
gptkb:chordin
|
|
gptkbp:bfsLayer
|
7
|