Müllerian inhibiting substance

URI: https://gptkb.org/entity/Müllerian_inhibiting_substance
GPTKB entity
Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:protein
hormone
gptkbp:abbreviation gptkb:AMH
gptkbp:alsoKnownAs anti-Müllerian hormone
gptkbp:associatedWith persistent Müllerian duct syndrome
gptkbp:discoveredBy Alfred Jost
gptkbp:discoveredIn 1947
gptkbp:expressedIn granulosa cells of ovary
gptkbp:familyMember transforming growth factor beta family
gptkbp:function inhibits development of female reproductive tract in males
regression of Müllerian ducts in male embryos
gptkbp:gene AMH gene
gptkbp:halfLife 2–7 days
https://www.w3.org/2000/01/rdf-schema#label Müllerian inhibiting substance
gptkbp:locatedOnChromosome gptkb:chromosome_19p13.3
gptkbp:measures blood
gptkbp:medicalUse diagnosis of polycystic ovary syndrome
assessment of testicular presence in infants
marker of ovarian reserve
gptkbp:OMIM 600957
gptkbp:presentIn humans
mammals
gptkbp:producedBy gptkb:Sertoli_cells
gptkbp:recipient AMH receptor type II
gptkbp:regulates folliculogenesis
gptkbp:structure gptkb:protein
gptkbp:UniProtID P03971
gptkbp:bfsParent gptkb:TGF-beta_superfamily
gptkbp:bfsLayer 7