fibrodysplasia ossificans progressiva
GPTKB entity
Statements (39)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:physicist
|
| gptkbp:bfsLayer |
6
|
| gptkbp:bfsParent |
gptkb:BMP-4
|
| gptkbp:acquired |
genetic testing
|
| gptkbp:affects |
muscles
connective tissue |
| gptkbp:can_be |
painful episodes
|
| gptkbp:can_lead_to |
loss of mobility
|
| gptkbp:caused_by |
severe disability
heterotopic ossification |
| gptkbp:complications |
respiratory issues
|
| gptkbp:current_use |
progressively worsens
|
| gptkbp:descendant |
autosomal dominant inheritance
|
| gptkbp:disease_resistance |
ossification of soft tissues
|
| gptkbp:first_described_by |
1864
Sir Alfred Bruns |
| gptkbp:genetic_diversity |
ACV R1 gene
affects fewer than 1 in 2 million people. |
| https://www.w3.org/2000/01/rdf-schema#label |
fibrodysplasia ossificans progressiva
|
| gptkbp:is_affected_by |
trauma
adults and children bone morphogenetic protein signaling |
| gptkbp:is_associated_with |
limb deformities
|
| gptkbp:is_characterized_by |
abnormal bone growth
soft tissue swelling bone in muscles |
| gptkbp:is_known_for |
FOP
progressive in nature |
| gptkbp:is_linked_to |
increased risk of complications
|
| gptkbp:is_often_associated_with |
muscle stiffness
stone man syndrome |
| gptkbp:is_often_used_in |
males
|
| gptkbp:is_studied_in |
gptkb:hospital
|
| gptkbp:managed_by |
symptomatic treatment
|
| gptkbp:rarity |
general population
|
| gptkbp:scientific_classification |
rare diseases
|
| gptkbp:social_responsibility |
clinical evaluation
other conditions |
| gptkbp:treatment |
gptkb:hospital
|