|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:activatedBy
|
gptkb:interleukin-2
gptkb:JAK_kinases
gptkb:interleukin-15
gptkb:prolactin
recombinant human growth hormone
interleukin-7
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
immunodeficiency
growth hormone insensitivity
|
|
gptkbp:encodedBy
|
gptkb:STAT5B_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000173757
6777
|
|
gptkbp:formsHeterodimerWith
|
gptkb:Stat5a
gptkb:Stat5b
|
|
gptkbp:fullName
|
gptkb:Signal_transducer_and_activator_of_transcription_5B
|
|
gptkbp:function
|
transcription factor
cytokine signaling
|
|
gptkbp:gene
|
gptkb:STAT5B
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
11367
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Stat5b
|
|
gptkbp:interactsWith
|
gptkb:JAK2
gptkb:CBP/p300
gptkb:PIAS_proteins
gptkb:SOCS_proteins
gptkb:GRB2
gptkb:NCoA-1
|
|
gptkbp:locatedOnChromosome
|
17q21.2
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:memberOf
|
gptkb:STAT_protein_family
|
|
gptkbp:molecularWeight
|
approximately 90 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:growth_hormone_insensitivity_syndrome
immunodeficiency 76
|
|
gptkbp:OMIM
|
604260
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Stat5b
|
|
gptkbp:PDB
|
gptkb:1Y1U
|
|
gptkbp:phosphorylates
|
tyrosine 699
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
acetylation
|
|
gptkbp:regulates
|
apoptosis
cell proliferation
lactation
immune response
sexual dimorphism in liver gene expression
|
|
gptkbp:UniProtID
|
gptkb:P51692
|
|
gptkbp:bfsParent
|
gptkb:STAT5B
|
|
gptkbp:bfsLayer
|
8
|