|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Organic_cation_transporter_1
gptkb:OCT1
|
|
gptkbp:associatedWith
|
metformin pharmacokinetics
drug response variability
|
|
gptkbp:biologicalProcess
|
transmembrane transporter activity
organic cation transport
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:encodedBy
|
SLC22A1 gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSP00000361322
GC06P160073
|
|
gptkbp:expressedIn
|
high in liver
low in intestine
moderate in kidney
|
|
gptkbp:foundIn
|
gptkb:kidney
liver
intestine
|
|
gptkbp:gene
|
gptkb:SLC22A1
|
|
gptkbp:HGNC_ID
|
10963
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P51692
|
|
gptkbp:InterPro
|
IPR002293
|
|
gptkbp:KEGGID
|
hsa:6581
|
|
gptkbp:length
|
554
|
|
gptkbp:locatedOnChromosome
|
6
|
|
gptkbp:location
|
6q25.3
|
|
gptkbp:OMIM
|
602607
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:protein_name
|
Solute carrier family 22 member 1
|
|
gptkbp:proteinFamily
|
PF02309
|
|
gptkbp:Reactome
|
R-HSA-425393
|
|
gptkbp:RefSeq
|
NP_003042.2
|
|
gptkbp:species
|
gptkb:human
|
|
gptkbp:subcellularLocation
|
basolateral membrane
|
|
gptkbp:transmembraneDomains
|
12
|
|
gptkbp:transportation
|
gptkb:metformin
gptkb:tetraethylammonium
drugs
organic cations
|
|
gptkbp:UniProtID
|
gptkb:P51692
|
|
gptkbp:bfsParent
|
gptkb:STAT5B
gptkb:STAT5
|
|
gptkbp:bfsLayer
|
8
|