|
gptkbp:instanceOf
|
gptkb:protein
transcription factor
|
|
gptkbp:alternativeName
|
gptkb:Specificity_protein_2
gptkb:Transcription_factor_Sp2
gptkb:SP-2
|
|
gptkbp:associatedWith
|
gptkb:neuroblastoma
gptkb:cancer
colorectal cancer
leukemia
prostate cancer
hepatocellular carcinoma
glioma
|
|
gptkbp:domain
|
zinc finger domain
|
|
gptkbp:encodedBy
|
gptkb:SP2_gene
|
|
gptkbp:Entrez_Gene_ID
|
6667
ENSG00000185591
|
|
gptkbp:function
|
transcriptional activation
regulation of gene expression
DNA binding
transcriptional repression
|
|
gptkbp:HGNC_ID
|
11242
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SP2 transcription factor
|
|
gptkbp:interactsWith
|
gptkb:SP1_transcription_factor
gptkb:SP3_transcription_factor
gptkb:SP4_transcription_factor
|
|
gptkbp:locale
|
gptkb:nucleus
|
|
gptkbp:locatedOnChromosome
|
17q21.3
|
|
gptkbp:memberOf
|
gptkb:Sp/KLF_family
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Pan_troglodytes
gptkb:Rattus_norvegicus
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
acetylation
|
|
gptkbp:regulates
|
gptkb:Bcl-2
gptkb:cyclin_D1
gptkb:p21
gptkb:c-Myc
gptkb:VEGF
apoptosis
cell proliferation
development
differentiation
immune response
cell cycle
inflammatory response
tumorigenesis
|
|
gptkbp:UniProtID
|
Q02086
|
|
gptkbp:bfsParent
|
gptkb:SP2_gene
gptkb:Transcription_factor_Sp2
|
|
gptkbp:bfsLayer
|
7
|