Statements (64)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:protein
|
gptkbp:bfsLayer |
5
|
gptkbp:bfsParent |
gptkb:Kirsten_rat_sarcoma_viral_oncogene_homolog
|
gptkbp:associated_with |
gptkb:healthcare_organization
farnesylation palmitoylation |
gptkbp:discovered_by |
Molecular biologists
|
gptkbp:established |
growth factors
|
gptkbp:family |
small GT Pases
|
gptkbp:function |
cell signaling
|
gptkbp:genetic_diversity |
common in tumors
|
gptkbp:has_role |
signal transduction
|
https://www.w3.org/2000/01/rdf-schema#label |
Ras proteins
|
gptkbp:interacts_with |
effector proteins
|
gptkbp:is_aimed_at |
therapeutic drugs
|
gptkbp:is_involved_in |
apoptosis
cell cycle regulation cell differentiation cell growth gene expression immune response neurotransmitter release protein synthesis cellular response to stress tumorigenesis cell survival angiogenesis cell adhesion cell migration metabolism regulation cellular response to DNA damage cellular response to bacterial infection cellular response to cytokines cellular response to hormones cellular response to hypoxia cellular response to ionizing radiation cellular response to mechanical stress cellular response to oxidative stress cellular response to temperature changes cellular response to viral infection cellular response to growth factor cellular response to cell-cell interactions cellular response to cell-matrix interactions cellular response to environmental changes cellular response to extracellular matrix cellular response to nutrients cellular response to metabolic changes cellular response to stress hormones cellular response to p H changes cellular response to cell density cellular response to cell shape changes cellular response to extracellular signals cellular response to growth inhibitors cellular response to intracellular signals cellular response to pathological changes cellular response to physiological changes |
gptkbp:is_recognized_by |
rat sarcoma
|
gptkbp:located_in |
plasma membrane
|
gptkbp:regulates |
MAPK pathway
P I3 K pathway |
gptkbp:repealed_by |
GAP proteins
|
gptkbp:type_of |
H-Ras
K-Ras N-Ras |