|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:activatedBy
|
cytokines
growth factors
stress signals
|
|
gptkbp:alias
|
gptkb:AP-1_transcription_factor_subunit_c-Fos
gptkb:c-Fos
Fos proto-oncogene, AP-1 transcription factor subunit
|
|
gptkbp:discoveredBy
|
gptkb:Harold_Varmus
gptkb:J._Michael_Bishop
gptkb:Inder_Verma
gptkb:Tom_Curran
gptkb:Michael_Karin
|
|
gptkbp:encodedBy
|
gptkb:FOS_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000170345
2353
|
|
gptkbp:expressedIn
|
gptkb:nucleus
|
|
gptkbp:firstDescribed
|
1983
|
|
gptkbp:form
|
gptkb:AP-1_transcription_factor
|
|
gptkbp:formsComplexWith
|
gptkb:c-Jun
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:HGNC_ID
|
HGNC:3796
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Proto-oncogene c-Fos
|
|
gptkbp:involvedIn
|
gptkb:cancer
osteosarcoma
cellular response to stimuli
|
|
gptkbp:locatedOnChromosome
|
14q24.3
|
|
gptkbp:memberOf
|
gptkb:Fos_family
|
|
gptkbp:OMIM
|
164810
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:phosphorylates
|
gptkb:MAPK
gptkb:ERK
|
|
gptkbp:regulates
|
gptkb:transformation
apoptosis
cell proliferation
differentiation
|
|
gptkbp:UniProtID
|
P01100
|
|
gptkbp:bfsParent
|
gptkb:FOS_gene
gptkb:Fos
gptkb:c-Fos
gptkb:c-fos_gene
gptkb:CFOS
|
|
gptkbp:bfsLayer
|
8
|