|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:activatedBy
|
stress
cytokines
growth factors
neurotransmitters
|
|
gptkbp:alias
|
gptkb:Proto-oncogene_c-Fos
gptkb:FOS
AP-1 transcription factor subunit
|
|
gptkbp:associatedWith
|
gptkb:cancer
osteosarcoma
neuronal plasticity
|
|
gptkbp:discoveredIn
|
1983
|
|
gptkbp:encodes
|
Fos protein
|
|
gptkbp:Entrez_Gene_ID
|
2353
|
|
gptkbp:expressedIn
|
transient
|
|
gptkbp:form
|
AP-1 transcription factor complex
|
|
gptkbp:formsComplexWith
|
c-Jun protein
|
|
gptkbp:function
|
signal transduction
cell cycle progression
immune response
learning and memory
oncogenesis
transcription regulation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:3796
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
c-fos gene
|
|
gptkbp:inducedBy
|
extracellular stimuli
|
|
gptkbp:locatedOn
|
gptkb:chromosome_14_(human)
|
|
gptkbp:memberOf
|
Fos gene family
|
|
gptkbp:mutationAssociatedWith
|
altered neuronal function
dysregulation in cancer
|
|
gptkbp:OMIM
|
164810
|
|
gptkbp:orthologIn
|
Fos (mouse)
|
|
gptkbp:product
|
gptkb:c-Fos_protein
|
|
gptkbp:referenceGenome
|
gptkb:NM_005252
|
|
gptkbp:regulates
|
gptkb:MAPK_pathway
gptkb:AP-1
apoptosis
cell proliferation
differentiation
neuronal activity
calcium signaling
CREB pathway
PKC pathway
immediate early gene
|
|
gptkbp:species
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:UniProtID
|
P01100
|
|
gptkbp:usedAs
|
marker of neuronal activity
|
|
gptkbp:bfsParent
|
gptkb:CREB
gptkb:Serum_response_factor
|
|
gptkbp:bfsLayer
|
7
|