Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
cytokines
growth factors phorbol esters stress signals |
| gptkbp:binds |
gptkb:gene
|
| gptkbp:composedOf |
gptkb:Fos_family_proteins
gptkb:Jun_family_proteins |
| gptkbp:discoveredIn |
1987
|
| gptkbp:domain |
basic leucine zipper domain
|
| gptkbp:function |
apoptosis
cell differentiation cell proliferation regulation of gene expression |
| gptkbp:GO_term |
GO:0003700
|
| gptkbp:inhibitedBy |
gptkb:glucocorticoids
|
| gptkbp:locatedIn |
gptkb:nucleus
|
| gptkbp:recognizedBy |
TRE DNA sequence
|
| gptkbp:regulates |
gptkb:immune_response
inflammation oncogenesis |
| gptkbp:relatedTo |
gptkb:cancer
gptkb:MAPK_signaling_pathway inflammatory diseases |
| gptkbp:subunit |
gptkb:c-Jun
gptkb:FosB gptkb:Fra-1 gptkb:Fra-2 gptkb:JunD gptkb:c-Fos gptkb:JunB |
| gptkbp:bfsParent |
gptkb:c-Jun_N-terminal_kinase_pathway
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
AP-1 transcription factor
|