|
gptkbp:instanceOf
|
gptkb:Ensembl_gene_ID
|
|
gptkbp:approvalYear
|
1997-12-05
|
|
gptkbp:approvedBy
|
gptkb:phosphatase_and_tensin_homolog
|
|
gptkbp:approvedSymbol
|
gptkb:PTEN
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Bannayan-Riley-Ruvalcaba_syndrome
gptkb:Cowden_syndrome
gptkb:Lhermitte-Duclos_disease
gptkb:endometrial_cancer
gptkb:glioblastoma
prostate cancer
|
|
gptkbp:dateModified
|
2022-03-10
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000171862
5728
|
|
gptkbp:function
|
gptkb:tumor_suppressor
negative regulation of PI3K/AKT pathway
phosphatase activity
regulation of apoptosis
regulation of cell cycle
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:9873
|
|
gptkbp:isTumorSuppressor
|
true
|
|
gptkbp:locatedOnChromosome
|
10
|
|
gptkbp:location
|
gptkb:10q23.31
|
|
gptkbp:locusType
|
gptkb:gene
gene with protein product
|
|
gptkbp:OMIM
|
601728
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Pten
|
|
gptkbp:previousSymbols
|
gptkb:MMAC1
gptkb:TEP1
|
|
gptkbp:proteinFamily
|
gptkb:protein_tyrosine_phosphatases
|
|
gptkbp:refersTo
|
gptkb:PTEN
|
|
gptkbp:RefSeq
|
gptkb:NM_000314
|
|
gptkbp:status
|
Approved
|
|
gptkbp:synonym
|
gptkb:BZS
gptkb:MGC11227
gptkb:MHAM
gptkb:PTEN1
|
|
gptkbp:UniProtID
|
gptkb:P60484
|
|
gptkbp:bfsParent
|
gptkb:RAS
|
|
gptkbp:bfsLayer
|
4
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HGNC:9873
|