|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Phosphatase_and_tensin_homolog
gptkb:MMAC1
gptkb:TEP1
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Bannayan-Riley-Ruvalcaba_syndrome
gptkb:Cowden_syndrome
gptkb:Lhermitte-Duclos_disease
gptkb:endometrial_cancer
gptkb:glioblastoma
gptkb:melanoma
prostate cancer
|
|
gptkbp:cellularComponent
|
gptkb:cell_membrane
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:discoveredIn
|
1997
|
|
gptkbp:discovery_method
|
molecular cloning
|
|
gptkbp:EC_number
|
3.1.3.67
|
|
gptkbp:Entrez_Gene_ID
|
ENSP00000371953
|
|
gptkbp:function
|
protein tyrosine phosphatase activity
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
|
|
gptkbp:gene
|
gptkb:PTEN
|
|
gptkbp:HGNC_ID
|
9588
|
|
gptkbp:KEGGID
|
hsa:5728
|
|
gptkbp:length
|
403 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:10q23.3
gptkb:chromosome_10q23.3
10
|
|
gptkbp:molecularWeight
|
47 kDa
|
|
gptkbp:OMIM
|
601728
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:PI3K-Akt_signaling_pathway
apoptosis
cell cycle regulation
|
|
gptkbp:PDB
|
gptkb:1D5R
gptkb:1D5V
gptkb:5BUG
|
|
gptkbp:postTranslationalModification
|
phosphorylation
oxidation
ubiquitination
|
|
gptkbp:RefSeq
|
NP_000305.3
|
|
gptkbp:reviewedBy
|
yes
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:subunit
|
gptkb:monomer
|
|
gptkbp:tissue_specificity
|
ubiquitous
|
|
gptkbp:UniProtID
|
gptkb:P60484
|
|
gptkbp:bfsParent
|
gptkb:HGNC:9873
|
|
gptkbp:bfsLayer
|
5
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P60484
|