gptkbp:instanceOf
|
gptkb:protein
|
gptkbp:alternativeName
|
cartilage
|
gptkbp:animalSource
|
gptkb:marine
bovine
porcine
|
gptkbp:component
|
basement membrane
extracellular matrix
|
gptkbp:composedOf
|
amino acids
|
gptkbp:deficiencyCauses
|
gptkb:scurvy
Ehlers-Danlos syndrome
osteogenesis imperfecta
|
gptkbp:degradedBy
|
collagenase
|
gptkbp:discoveredBy
|
gptkb:Glen_E._Francis
|
gptkbp:encodedBy
|
gptkb:COL1A1_gene
gptkb:COL1A2_gene
gptkb:COL2A1_gene
gptkb:COL3A1_gene
gptkb:COL4A1_gene
gptkb:COL5A1_gene
|
gptkbp:firstDescribed
|
1930s
|
gptkbp:foundIn
|
gptkb:bone
gptkb:skin
gptkb:skeletal_muscle
teeth
collagen
cornea
blood vessels
ligaments
tendons
|
gptkbp:function
|
provides structural support
aids in tissue repair
contributes to tissue strength
influences cell adhesion
influences cell migration
influences tissue development
|
gptkbp:hasType
|
gptkb:Type_III_collagen
gptkb:Type_II_collagen
gptkb:Type_IV_collagen
gptkb:Type_I_collagen
gptkb:Type_V_collagen
|
gptkbp:medicalUse
|
biomaterials
collagen injections
scaffold for tissue regeneration
|
gptkbp:richIn
|
glycine
hydroxyproline
proline
|
gptkbp:solubility
|
insoluble in water
|
gptkbp:structure
|
triple helix
|
gptkbp:synthesisType
|
fibroblasts
|
gptkbp:usedIn
|
gptkb:physician
tissue engineering
dietary supplements
wound healing
food industry
gelatin production
|
gptkbp:bfsParent
|
gptkb:bronchioles
gptkb:bone
gptkb:Macromolecules
gptkb:PTEN
gptkb:rhabdomyosarcoma
gptkb:Axis_(anatomy)
|
gptkbp:bfsLayer
|
5
|