|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:B-50
F1 protein
Growth Associated Protein 43
neuromodulin
|
|
gptkbp:associatedWith
|
neuroplasticity
learning and memory
axon guidance
neuroregeneration
|
|
gptkbp:Entrez_Gene_ID
|
2596
|
|
gptkbp:expressedIn
|
development
central nervous system
peripheral nervous system
nerve injury
|
|
gptkbp:firstDescribed
|
1980s
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkb:Rattus_norvegicus
|
|
gptkbp:function
|
gptkb:synaptic_plasticity
neural development
nerve regeneration
axonal growth
|
|
gptkbp:gene
|
GAP43
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GAP-43
|
|
gptkbp:interactsWith
|
gptkb:calmodulin
actin cytoskeleton
|
|
gptkbp:locatedIn
|
neuronal growth cones
|
|
gptkbp:locatedOnChromosome
|
3q13.31 (human)
|
|
gptkbp:molecularWeight
|
43 kDa
|
|
gptkbp:mutationAssociatedWith
|
defective neural development
impaired axonal regeneration
|
|
gptkbp:OMIM
|
602005
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:phosphorylates
|
gptkb:protein_kinase_C
|
|
gptkbp:regulates
|
neurite outgrowth
synaptic efficacy
|
|
gptkbp:relatedTo
|
gptkb:Alzheimer's_disease
neurodevelopmental disorders
spinal cord injury
|
|
gptkbp:sequence
|
protein-coding
|
|
gptkbp:structure
|
intrinsically disordered protein
N-terminal myristoylation
phosphorylation site at Ser41
|
|
gptkbp:subcellularLocation
|
gptkb:plasma_membrane
growth cone membrane
|
|
gptkbp:UniProtID
|
P17677
|
|
gptkbp:bfsParent
|
gptkb:PKCĪ±
gptkb:protein_kinase_C
gptkb:PKC_alpha
gptkb:PKC_epsilon
gptkb:PRKCB
gptkb:PRKCE
gptkb:Protein_kinase_C
gptkb:protein_kinase_C_(PKC)
|
|
gptkbp:bfsLayer
|
7
|