|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
PKA C-alpha
PKAC-alpha
cAMP-dependent protein kinase catalytic subunit alpha
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Cushing's_syndrome
adrenocortical adenoma
|
|
gptkbp:encodes
|
cAMP-dependent protein kinase catalytic subunit alpha
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000139318
5566
|
|
gptkbp:fullName
|
protein kinase cAMP-activated catalytic subunit alpha
|
|
gptkbp:function
|
phosphorylates serine/threonine residues
catalytic subunit of protein kinase A
|
|
gptkbp:HGNC_ID
|
9380
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PRKACA
|
|
gptkbp:involvedIn
|
gptkb:cAMP_signaling_pathway
cell proliferation
regulation of metabolism
gene transcription regulation
|
|
gptkbp:length
|
350 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19
|
|
gptkbp:molecularWeight
|
40 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Prkaca
|
|
gptkbp:postTranslationalModification
|
phosphorylation
myristoylation
|
|
gptkbp:RefSeq
|
NM_002730
|
|
gptkbp:regulates
|
activated by cAMP
inhibited by regulatory subunits of PKA
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
mitochondrion
|
|
gptkbp:UniProtID
|
P17612
|
|
gptkbp:bfsParent
|
gptkb:PKCĪ±
gptkb:protein_kinase_A
|
|
gptkbp:bfsLayer
|
7
|