|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
gptkb:Transforming_protein_p21
|
|
gptkbp:biologicalProcess
|
cell proliferation
signal transduction
GTP binding
GTPase activity
|
|
gptkbp:EC_number
|
3.6.5.2
|
|
gptkbp:Entrez_Gene_ID
|
3265
ENSP00000261799
|
|
gptkbp:function
|
Molecular switch in signal transduction
|
|
gptkbp:gene
|
gptkb:HRAS
|
|
gptkbp:hasCellularComponent
|
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:hasDiseaseAssociation
|
gptkb:cancer
gptkb:Bladder_cancer
gptkb:Costello_syndrome
gptkb:Gastric_cancer
|
|
gptkbp:hasGeneName
|
gptkb:HRAS
|
|
gptkbp:hasIsoform
|
P01135-1
P01135-2
|
|
gptkbp:hasPfamID
|
gptkb:PF00071
|
|
gptkbp:hasRefSeqProteinID
|
gptkb:NP_005334.1
|
|
gptkbp:hasSequenceLength
|
189
|
|
gptkbp:hasTaxonomyID
|
9606
|
|
gptkbp:HGNC_ID
|
5173
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P01135
|
|
gptkbp:InterPro
|
gptkb:IPR001806
|
|
gptkbp:isOncogene
|
true
|
|
gptkbp:KEGGID
|
gptkb:hsa:3265
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
|
|
gptkbp:OMIM
|
190020
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:Ras_signaling_pathway
|
|
gptkbp:PDB
|
gptkb:5P21
1AA9
4Q21
|
|
gptkbp:postTranslationalModification
|
Farnesylation
Palmitoylation
Phosphorylation
|
|
gptkbp:Reactome
|
gptkb:R-HSA-5673001
|
|
gptkbp:subcellularLocation
|
gptkb:Cell_membrane
Endomembrane system
|
|
gptkbp:UniProt_entry_name
|
gptkb:HRAS
|
|
gptkbp:UniProtID
|
gptkb:P01135
|
|
gptkbp:bfsParent
|
gptkb:TGF-alpha
gptkb:transforming_growth_factor_alpha_(TGF-α)
gptkb:transforming_growth_factor_alpha
|
|
gptkbp:bfsLayer
|
7
|