|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
Yes
|
|
gptkbp:associatedWith
|
gptkb:Melanoma
Noonan syndrome 6
Acute myeloid leukemia
Juvenile myelomonocytic leukemia
|
|
gptkbp:database
|
gptkb:GeneCards
gptkb:NCBI_Gene
gptkb:UniProt
gptkb:Ensembl
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000213281
4893
|
|
gptkbp:enzymeClassification
|
gptkb:EC_3.6.5.2
|
|
gptkbp:family
|
gptkb:Ras_family
|
|
gptkbp:fullName
|
GTPase NRas
|
|
gptkbp:function
|
GTP-binding protein involved in signal transduction
|
|
gptkbp:gene
|
gptkb:NRAS
|
|
gptkbp:GO
|
gptkb:plasma_membrane
GTP binding
MAPK cascade
signal transducer activity
|
|
gptkbp:hasIsoform
|
2
|
|
gptkbp:HGNC_ID
|
7989
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P01111 (NRAS)
|
|
gptkbp:interactsWith
|
gptkb:BRAF
gptkb:GRB2
gptkb:PIK3CA
gptkb:RAF1
gptkb:SOS1
|
|
gptkbp:length
|
189 amino acids
|
|
gptkbp:locatedOnChromosome
|
1
|
|
gptkbp:location
|
1p13.2
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:G13
gptkb:G12
Q61
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
Danio rerio nras
Mus musculus Nras
Rattus norvegicus Nras
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:Ras_signaling_pathway
|
|
gptkbp:PDB
|
gptkb:3CON
gptkb:5UHV
6ZWL
|
|
gptkbp:postTranslationalModification
|
Farnesylation
Palmitoylation
|
|
gptkbp:RefSeq
|
NP_002515.1
|
|
gptkbp:reviewedBy
|
Yes
|
|
gptkbp:subcellularLocation
|
gptkb:Cell_membrane
gptkb:Cytoplasm
gptkb:Golgi_apparatus
|
|
gptkbp:UniProtID
|
gptkb:P01111
|
|
gptkbp:bfsParent
|
gptkb:RAS_gene
|
|
gptkbp:bfsLayer
|
5
|