|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:NEDD4-1
gptkb:E3_ubiquitin-protein_ligase_NEDD4
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
hypertension
|
|
gptkbp:discoveredBy
|
Peter C. L. Beverley
|
|
gptkbp:discoveredIn
|
1992
|
|
gptkbp:domain
|
gptkb:WW_domain
gptkb:HECT_domain
C2 domain
|
|
gptkbp:encodedBy
|
gptkb:NEDD4_gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000133119
|
|
gptkbp:fullName
|
Neural precursor cell expressed developmentally down-regulated protein 4
|
|
gptkbp:function
|
gptkb:E3_ubiquitin-protein_ligase
|
|
gptkbp:HGNC_ID
|
7727
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NEDD4
|
|
gptkbp:involvedIn
|
gptkb:ubiquitin-proteasome_pathway
|
|
gptkbp:length
|
900
|
|
gptkbp:locatedOnChromosome
|
15q21.3
|
|
gptkbp:molecularWeight
|
102 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:regulates
|
gptkb:SMAD2
gptkb:AKT
gptkb:PTEN
gptkb:ENaC
|
|
gptkbp:subcellularLocation
|
gptkb:cell_membrane
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
P46934
|
|
gptkbp:bfsParent
|
gptkb:NEDD4-1
|
|
gptkbp:bfsLayer
|
6
|