Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
protein
|
| gptkbp:function |
cell signaling
|
| gptkbp:hasPerformedAt |
AKT1
AKT2 AKT3 |
| gptkbp:hasRecognition |
target for cancer therapy
biomarker for cancer prognosis involved in cardiovascular diseases involved in metabolic syndrome involved in neurodegenerative diseases involved in obesity involved in wound healing involved in drug resistance involved in aging involved in autoimmune diseases involved in chronic diseases involved in fat storage involved in inflammatory diseases involved in insulin resistance involved in metabolic disorders involved in muscle growth involved in stem cell biology involved in tissue regeneration potential target for diabetes treatment |
| gptkbp:hasRole |
apoptosis
cell proliferation glucose metabolism lipid metabolism protein synthesis tumorigenesis angiogenesis insulin_signaling |
| https://www.w3.org/2000/01/rdf-schema#label |
AKT
|
| gptkbp:interactsWith |
gptkb:PI3K
mTOR GSK3B |
| gptkbp:involvedIn |
metabolism
cell growth cell survival |
| gptkbp:isAssociatedWith |
cancer
|
| gptkbp:isEngagedIn |
gptkb:PTEN
gptkb:TSC1/TSC2 |
| gptkbp:isLocatedIn |
various tissues
|
| gptkbp:isPartOf |
PI3K/AKT signaling pathway
|
| gptkbp:isRegulatedBy |
growth factors
cytokines hormones |
| gptkbp:isVisitedBy |
phosphorylation
|
| gptkbp:locatedIn |
cytoplasm
|