Statements (67)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
PI3 K pathway
|
| gptkbp:clinical_trial |
target for cancer therapy
biomarker for diabetes involved in resistance to chemotherapy |
| gptkbp:discovered_by |
gptkb:William_C._H._Lee
1990s |
| gptkbp:function |
involved in glucose metabolism
regulates cell survival promotes cell growth |
| https://www.w3.org/2000/01/rdf-schema#label |
AKT
|
| gptkbp:initiated_by |
AZD5363
MK-2206 Perifosine GSK690693 |
| gptkbp:interacts_with |
gptkb:m_TOR
gptkb:Raptor gptkb:PTEN gptkb:p53 BAD TSC2 FOXO1 Rictor GSK3 B |
| gptkbp:involved_in |
gptkb:Vision
gptkb:neurodegenerative_diseases reproductive health apoptosis regulation cardiac function cell proliferation cellular metabolism immune response neurotransmitter release inflammation metabolic syndrome wound healing muscle growth neuroplasticity stress response synaptic plasticity cellular differentiation skin health angiogenesis taste perception aging process fat metabolism tissue repair cell migration stem cell maintenance bone metabolism hormonal signaling olfactory function hair follicle cycling |
| gptkbp:location |
gptkb:Atom
cytoplasm |
| gptkbp:pathway |
Cell cycle regulation
Insulin signaling pathway m TOR signaling pathway |
| gptkbp:promoter |
gptkb:AKT1
AKT2 AKT3 |
| gptkbp:related_to |
gptkb:diabetes
gptkb:Oncology cardiovascular diseases |
| gptkbp:type |
serine/threonine kinase
|
| gptkbp:bfsParent |
gptkb:Akash_Network
|
| gptkbp:bfsLayer |
5
|